Dextrostat Withdrawal

Dextrostat Withdrawal

Dextrostat is a previously available brand-name version of dextroamphetamine. It continues to be available in generic form, and it is used to treat attention-deficit hyperactivity disorder, or ADHD, narcolepsy, and other sleep disorders as a prescription drug. 1

Amphetamines such as Dextrostat have a high potential for abuse, and long-term use can lead to the development of physiological dependence, a phenomenon that renders the body incapable of functioning adequately without the drug. 1

When people who have a significant Dextrostat dependence suddenly slow or stop using the drug, they may experience withdrawal symptoms, especially if they have taken the drug over a long period of time or in large doses. 4 Some of these symptoms are potentially serious, and in these instances, withdrawal may be best managed by medical or addiction treatment professionals.

Someone who has consistently abused Dexedrine or is addicted to it should seek continued treatment after detox to help minimize the chances of relapse and other consequences of abuse.

Withdrawal Symptoms of Dextrostat

Some of the withdrawal symptoms a person may experience when they stop taking Dextrostat or reduce the dose include:

  • Depression.
  • Cravings.
  • Increased appetite.
  • Headaches.
  • Tiredness or weakness.
  • Problems sleeping. 2,3,4

These symptoms will vary in length and intensity depending on how frequently the person used Dextrostat, how long they used it, whether they have any physical or mental health problems, and how much they were taking.

How Long Does Dextrostat Withdrawal Last?

The timeline for each person is different, depending on their Dextrostat use. Most people experience symptoms of withdrawal 1 to 3 days after their last dose of Dextrostat. Symptoms usually peak in 4-7 days, but they can last up to 4 weeks. 4

Learn more about Dextrostat withdrawal symptoms.

Withdrawing From Dextrostat: Treatment Methods and Options for Help

Dextrostat withdrawal treatment can help reduce withdrawal side effects. Options for Dextrostat withdrawal treatment include:

  • Detox centers.
  • Inpatient rehab programs.
  • Outpatient rehab programs.

These programs offer different levels of supervision, intensity, and required time commitment. Detox centers, for example, only provide treatment for withdrawal, while inpatient programs may offer detox and a full suite of addiction recovery services, including individual and group counseling, medical care, and 12-step meetings for a period of 30 days or longer.

These programs can also prescribe medications to treat symptoms such as depression and insomnia.

Detoxification may include tapering, where the dose of the drug is reduced over time and eventually stopped completely.

How Long Does It Take to Detox From Dextrostat?

Dextrostat detox can take anywhere from 4-7 days, though people can continue to have symptoms for up to 4 weeks. 4

Learn more about options for Dextrostat withdrawal help.

Treatment for Dextrostat Withdrawal

In many cases, people recovering from amphetamine dependence or addiction will progress through 3 major phases of treatment.

  • Detox. First, a person will participate in detoxification. This stage could take a number of days depending on the number of amphetamines in the system.
  • Rehab. Once the detoxification is completed, people enroll in either an inpatient/residential or outpatient rehabilitation program. Structured rehab programs may include a number of different activities, such as therapy sessions, group-talk and discussion, relapse prevention courses, and sessions on addiction. The point of the treatment phase is to help the person develop positive, drug-free habits that they can incorporate into their day-to-day lives.
  • Aftercare. As a third phase, after completion of the initial course of rehab, people may continue outpatient group or individual therapy or stay in a sober living home. The continuation of therapy after rehab often helps reduce the chances of relapse for many people.

Benefits of the varying types of recovery programs include the around-the-clock care an inpatient service provides, or the ability to come and go from an outpatient clinic.

Can You Detox From Dextrostat Safely at Home?

Home remedies are not proven to relieve withdrawal symptoms. It is best to seek formal treatment.

Additionally, some people may become very depressed during withdrawal, while others may have psychological problems such as hallucinations and mental confusion. These issues are best treated in a detox program. 4

How Long Does Dextrostat Withdrawal Last?

The timeline for each person is different, depending on their Dextrostat use. Most people experience symptoms of withdrawal 1 to 3 days after their last dose of Dextrostat. Symptoms usually peak in 4-7 days, but they can last up to 4 weeks. 4

Dextrostat Information at a Glance
Medication Name, Costs Class of Medicine
Generic Name: dextroamphetamine sulfate
Brand Name: Dextrostat, Dexedrine, ProCentra
Cost/Price:  $0.25 per 5 mg tablet; $0.48 per 10 mg tablet 1
Used to Treat Addiction? No
Function or Use: treatment of narcolepsy and attention-deficit hyperactivity disorder (ADHD) 2
Type of Drug: central nervous system (CNS) stimulant 2
Duration of Action: several hours
Form, Intake, and Dose Interactions and Complications
Drug Forms: 5 mg, 10 mg tabs 1
Administration Routes: administered orally 1
Overdose Symptoms: restlessness, tremors, confusion, hallucinations, panic states, fatigue, depression, vomiting, convulsions, coma. 1
Alcohol Interaction: increases the risk of alcohol poisoning or alcohol-related injuries. 7
Prescription Medications: may interact with acidifying agents, urinary acidifying agents, alkalinizing agents, antidepressants, MAO inhibitors, antihistamines, chlorpromazine, ethosuximide, haloperidol, lithium carbonate, meperidine, methenamine, norepinephrine, phenobarbital, phenytoin, veratrum alkaloids, adrenergic blockers, and antihypertensives 6
Contraindications: cardiovascular disease, moderate hypertension, arteriosclerosis, exaggerated response to the sympathomimetic amines (e.g., epinephrine), glaucoma, agitated states, history of drug abuse 4
Effects and Adverse Reactions Substance Abuse
Short-Term: higher blood pressure, restlessness, dizziness, euphoria, dysphoria, headache, insomnia, tremors, diarrhea, constipation 6
Long-Term: changes in libido, impotence, slowed growth in children 2,6
Risk of Substance Abuse: High 4
Signs of Abuse: strong cravings, changes in blood pressure, mood swings, irritability
Physiological Problem Signs and Symptoms Dependence and Addiction Issues
Withdrawal Syndrome Onset: few hours to several days after the last use 5
Withdrawal Symptoms: fatigue, vivid dreams, insomnia or hypersomnia, increased appetite, psychomotor agitation, depression, suicidal ideation 5
Tolerance: Yes 5
Physical Dependence: High 5
Psychological Dependence: High 5
Legal Schedules and Ratings
Controlled Substances Act Rating: Schedule II 6


[1]. National Library of Medicine. DailyMed. (2005). Dextrostat (Dextroamphetamine Sulfate) Tablet. 

[2]. Mayo Clinic. (2016). Dextroamphetamine (Oral Route).

[3]. National Institute on Drug Abuse (NIDA). (2014). Stimulant ADHD Medications: Methylphenidate and Amphetamines.

[4]. McKeith, R. and McKenna, S. (2000). Amphetamine Dependence & Withdrawal. GP Drug & Alcohol Supplement 12.

Dextrostat Information at a Glance Sources

[1]. DrugBank. (n.d.). Dextroamphetamine.

[2]. U.S. Library of Medicine. (2016). Dextroamphetamine.

[3]. U.S. Food and Drug Administration. (n.d.). Drugs@FDA: FDA Approved Drug Products.

[4]. Med Library. (2008). Dextrostat.

[5]. American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Washington, D.C.:  American Psychiatric Publishing.

[6]. U.S. Food and Drug Administration. (n.d.). Dextrostat.

[7]. Substance Abuse and Mental Health Services Administration (SAMHSA). Prescription Drug Misuse Among College Students.