Depade, a brand-name version of Naloxone, is a medication commonly used to help treat opioid addiction. It enters the brain and helps curb the cravings that people face when trying to get sober.
While Depade can’t free someone of an addiction entirely, it does make the desirable effects of opiate drugs (happiness, euphoria) much less intense. As a result, it also (hopefully) makes the urge to use much less intense.
The Pharmacology of Depade
Depade is able to block receptors in the brain that signal the release of dopamine, the neurotransmitter that regulates our senses of reward and pleasure.
While this seems like a straight forward path to success in reducing opioid dependence, there are both pros and cons to using a medication like Depade. Explore our lists below to learn more about potential benefits and risk of taking this unique medication.
Let's Look at the Pros
- Depade has been shown to reduce, with opioid use, or completely eradicate, as found with alcohol dependency, the intensity of cravings to help aid individuals who are trying to end their opioid or alcohol addictions.
- Depade decreases the desirable effects of opioids, making the use of these drugs far less tempting.
- By helping to curb intense cravings, Depade provides the individual with a mental and emotional break, where they can focus on health and recovery beyond the use of opioids.
- Depade blocks the release of certain neurotransmitters in the brain, providing a chemical solution to the dependency that has developed in the brain.
- As Depade aims to reduce cravings for opioids, it has the farther reaching effect of reducing the urge to use other drugs, as well.
Let's Look at the Cons
- Like all medications, adverse side effects such as extreme tiredness, nervousness, anxiety, restlessness, stomach cramps, pain, sleeping issues, headaches, nausea, and vomiting can occur with Depade.
- Internal organ damage, even death, can occur when used in conjunction with other painkillers or illegal drugs.
- As with the use of any new drug, doctor consultation is required. Depade is only available through prescription from a doctor.
- Before taking Depade, patients must abstain from any opioid use for 7 days, which can be very challenging. Once these milestones have been reached, however, Depade can be prescribed to provide assistance in staying sober.
- While Depade can provide chemical assistance in the journey to get sober, it is not a replacement for the holistic lifestyle changes that an addict must make in order to maintain long-term sobriety.
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